Search results for "Spasmodic Torticollis"

showing 3 items of 3 documents

Effects of botulinum toxin type A on vibration induced facilitation of motor evoked potentials in spasmodic torticollis.

2004

It has not been clarified if botulinum toxin (BTX) injection leads to muscle spindle dysfunction in man. This study aimed to test the hypothesis that BTX application reduces the facilitation of a magnetic evoked response (MEP).We used the vibration induced facilitation of an MEP of the sternocleidomastoid muscle (SCM) as a surrogate marker for muscle spindle function in 20 healthy subjects and 10 patients with idiopathic rotational torticollis in whom BTX was injected unilaterally.The increase in the amplitude and area of the MEPs in the clinically not affected and untreated SCM of the patients did not differ significantly from the controls. At baseline, the vibration induced increase in th…

AdultMalePapermedicine.medical_specialtyMuscle spindleSpasmodic Torticolliscomplex mixturesInjections IntramuscularVibrationNeck MusclesMedicineHumansBotulinum Toxins Type ATorticollisAgedDenervationMuscle DenervationDose-Response Relationship Drugbusiness.industryMiddle Agedmedicine.diseaseEvoked Potentials MotorBotulinum toxinMuscle DenervationSurgeryNerve RegenerationPsychiatry and Mental healthmedicine.anatomical_structureNeuromuscular AgentsAnesthesiaSurgeryFemaleNeurology (clinical)businessSternocleidomastoid musclemedicine.drugTorticollisReinnervationJournal of neurology, neurosurgery, and psychiatry
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Sudomotor testing predicts the presence of neutralizing botulinum A toxin antibodies.

2002

The increasing number of patients being treated with botulinum toxin A complex (BoNT/A) has led to a higher incidence of neutralizing anti-BoNT/A antibodies (ABAs). Because BoNT/A is known to inhibit sweating, here we report sudometry as a possibility for predicting the presence of ABA. Sixteen patients suffering from spasmodic torticollis were selected: in 2 patients, BoNT/A treatment continued to be effective, in 9 patients, the treatment effect was impaired, and in 5 patients, secondary treatment failure developed. BoNT/A (100 mouse units, Dysport; Ipsen Pharma, Berkshire, United Kingdom) was injected subcutaneously into the lateral calves. Sweating was visualized with iodine starch stai…

AdultMalemedicine.medical_specialtySpasmodic TorticollisSweatingIn Vitro Techniquesmedicine.disease_causeGastroenterologyStatistics NonparametricCentral nervous system diseaseMicePredictive Value of TestsInternal medicinemedicineAnimalsHumansBotulinum Toxins Type ATorticollisAgedHypohidrosisbiologyToxinbusiness.industryMiddle Agedmedicine.diseaseAntibodies BacterialSudomotorNeurologyImmunologybiology.proteinClostridium botulinumAxon reflexFemaleNeurology (clinical)AntibodybusinessTorticollisAnnals of neurology
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Presurgical evaluation of hemifacial spasm and spasmodic torticollis caused by a neurovascular conflict from AICA with 3T MRI integrated by 3D drive …

2014

Background: Hemifacial spasm (HS) and spasmodic torticollis (ST) are well-known disorders that are caused by a neurovascular conflict. HS is characterized by irregular, involuntary muscle contractions on one side of the face due to spasms of orbicularis oris and orbicularis oculi muscles, and is usually caused by vascular compression of the VII cranial nerve. ST is an extremely painful chronic movement disorder causing the neck to involuntary turn to the side, upward and/or downward. HS is usually idiopathic but it is rarely caused by a neurovascular conflict with the XI cranial nerve. Case Description: We present a case of a 36-year-old woman with a 2-year history of left hemifacial spasm …

medicine.medical_specialtymicrovascular decompressionmedicine.medical_treatmenttransfixing arterySpasmodic TorticollisMicrovascular decompressionCase Reportspasmodic torticollisneurovascular conflictmedicineHemifacial spasm; microvascular decompression; neurovascular conflict; spasmodic torticollis; transfixing arteryHemifacial spasm microvascular decompression neurovascular conflict spasmodic torticollis transfixing arterymedicine.diagnostic_testbusiness.industrySettore MED/27 - NeurochirurgiaCranial nervesMagnetic resonance imagingNeurovascular bundlemedicine.diseaseFacial nerveSurgerymedicine.anatomical_structureHemifacial spasmspasmodic torticolliSurgeryNeurology (clinical)businessCerebellar arteryHemifacial spasm
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